Supplementary Information for Coghlan and Wolfe (2004)

Methods

For details of the methods, see here.

Note that introns are numbered from left to right along the sense strand of the gene (not from 5' to 3' in the gene).

Novel Introns in C. briggsae

1. CBG01087.F.6 in CBG01087 (ortholog Y50D4A.4, unknown function) tree alignment
2. CBG02276.R.7 in CBG02276 (ortholog R05F9.12, carbohydrate metabolism) tree alignment
3. CBG02970.R.4 in CBG02970 (ortholog C09H10.3, complex I : NADH to ubiquinone) tree alignment
4. CBG03054.F.3 in CBG03054 (ortholog C14A4.13, protein amino acid phosphorylation) tree alignment
5. CBG03989.R.2 in CBG03989 (ortholog Y74C10AM.1, transport : ATP-binding) tree alignment
6. CBG03991.F.3 in CBG03991 (ortholog Y74C10AR.1, homolog of human initiation factor) tree alignment
7. CBG04120.R.2 in CBG04120 (ortholog Y71F9B.7, cell cycle; protein amino acid phosphorylation) tree alignment
8. CBG04332.R.8 in CBG04332 (ortholog F02E11.1, transport; ATP-binding) tree alignment
9. CBG05238.F.2 in CBG05238 (ortholog F09A5.1, transport; sugar-binding) tree alignment
10. CBG06975.R.1 in CBG06975 (ortholog T25D3.3, amino acid metabolism; proteolysis and peptidolysis) tree alignment
11. CBG08388.F.7 in CBG08388 (ortholog F01D4.1, metabolism) tree alignment
12. CBG08494.R.5 in CBG08494 (ortholog Y48G8AL.6, nonsense-mediated decay; RNA interference; genital morphogenesis) tree alignment
13. CBG09872.R.3 in CBG09872 (ortholog ZK1128.4, DNA repair; transcription regulation) tree alignment
14. CBG11248.R.2 in CBG11248 (ortholog F52E1.10, proton transport) tree alignment
15. CBG12264.R.1 in CBG12264 (ortholog ZK688.3, metabolism) tree alignment
16. CBG12289.F.6 in CBG12289 (ortholog ZK688.8, homolog of human N-acetylgalactosaminyltransferase) tree alignment
17. CBG12498.F.3 in CBG12498 (ortholog F43G9.9, homolog of yeast calponin) tree alignment
18. CBG12877.F.2 in CBG12877, homolog of human NOGO-interacting mitochondrial protein (ortholog TBLASTN hit) tree alignment
19. CBG13586.R.1 in CBG13586 (ortholog K08D12.1, ubiquitin-dependent protein degradation) tree alignment
20. CBG14784.R.4 in CBG14784 (ortholog R07E4.4, homolog of yeast nucleoside diphosphatase) tree alignment
21. CBG15267.F.3 in CBG15267 (ortholog T19C3.8, protein amino acid dephosphorylation) tree alignment
22. CBG15720.R.6 in CBG15720 (ortholog Y50D7A.6, homolog of human kinesin-like protein) tree alignment
23. CBG15756.R.5 in CBG15756 (ortholog Y37D8A.22, unknown function) tree alignment
24. CBG16436.R.2 in CBG16436 (ortholog F21D5.7, protein targeting) tree alignment
25. CBG16503.F.5 in CBG16503 (ortholog F11H8.1, protein modification; ubiquitin cycle) tree alignment
26. CBG17774.R.9 in CBG17774 (ortholog F18A12.8, proteolysis and peptidolysis) tree alignment
27. CBG17959.F.2 in CBG17959 (ortholog C35D10.10, electron transport) tree alignment
28. CBG18137.R.2 in CBG18137 (ortholog ZK1236.1, protein synthesis elongation) tree alignment
29. CBG18597.F.3 in CBG18597 (ortholog F28F8.2, metabolism; transport) tree alignment
30. CBG18947.R.1 in CBG18947 (ortholog W01A11.5, homolog of human carnitine palmitoyltransferase) tree alignment
31. CBG19441.F.6 in CBG19441 (ortholog H15N14.2, homolog of human vesicle-fusing ATPase) tree alignment
32. CBG19800.F.2 in CBG19800 (ortholog Y105E8B.5, nucleoside metabolism; purine salvage) tree alignment
33. CBG20408.F.3 in CBG20408 (ortholog F49D11.1, homolog of human pre-mRNA splicing factor PRP17) tree alignment
34. CBG21228.F.4 in CBG21228 (ortholog T08A11.2, homolog of human splicing factor 3B subunit 1) tree alignment
35. CBG21228.F.7 in CBG21228 (ortholog T08A11.2, homolog of human splicing factor 3B subunit 1) tree alignment
36. CBG21228.F.8 in CBG21228 (ortholog T08A11.2, homolog of human splicing factor 3B subunit 1) tree alignment
37. CBG22093.F.7 in CBG22093 (ortholog Y37E3.17, electron transport; transport) tree alignment
38. CBG22999.F.3 in CBG22999 (ortholog Y39E4B.1, electron transport; transport) tree alignment
39. CBG23047.R.2 in CBG23047 (ortholog Y75B8A.14, homolog of mouse ATP-binding protein) tree alignment
40. CBG23281.F.4 in CBG23281 (ortholog W05E10.4, trehalose metabolism) tree alignment
41. CBG23817.F.1 in CBG23817 (ortholog Y80D3A.9, unknown function) tree alignment

Novel Introns in C. elegans

42. B0285.6.F.7 in B0285.6, sodium transport (ortholog CBG18085) tree alignment
43. B0432.4.F.3 in B0432.4, transport (ortholog CBG07018) tree alignment
44. C04G2.6.F.13 in C04G2.6, homolog of human mitotic control protein (ortholog CBG13499) tree alignment
45. C04G2.6.F.6 in C04G2.6, homolog of human mitotic control protein (ortholog CBG13499) tree alignment
46. C06E1.10.R.5 in C06E1.10, homolog of Arabidopsis putative pre-mRNA splicing factor (ortholog CBG15333) tree alignment
47. C25D7.7.R.5 in C25D7.7, signal transduction (ortholog CBG11577) tree alignment
48. C34B7.2.F.4 in C34B7.2, unknown function (ortholog CBG04077) tree alignment
49. D2024.6.R.1 in D2024.6, actin cytoskeleton organization and biogenesis (ortholog CBG05812) tree alignment
50. D2096.3.F.5 in D2096.3, carbohydrate metabolism (ortholog CBG18464) tree alignment
51. F02E11.1.F.1 in F02E11.1, transport (ortholog CBG04332) tree alignment
52. F10C1.7A.F.4 in F10C1.7A, homolog of human lamin (ortholog CBG02493) tree alignment
53. F10G8.6.F.1 in F10G8.6, homolog of human nucleotide binding protein (ortholog CBG03788 tree alignment
54. F16D3.1.F.5 in F16D3.1, microtubule-based movement (ortholog CBG04075) tree alignment
55. F20B6.2.F.2 in F20B6.2, ATP biosynthesis; proton transport (ortholog CBG14362) tree alignment
56. F29F11.1.R.2 in F29F11.1, electron transport (ortholog CBG09668) tree alignment
57. F32D1.5.R.1 in F32D1.5, nucleotide metabolism (ortholog CBG23625) tree alignment
58. F33H2.5.R.8 in F33H2.5, DNA replication (ortholog CBG19758) tree alignment
59. F36A4.7.F.8 in F36A4.7, gastrulation; transcription from Pol II promoter (ortholog CBG05355) tree alignment
60. F38E11.5.F.7 in F38E11.5, homolog of yeast protein involved in endoplasmic-to-Golgi protein trafficking (ortholog CBG21666) tree alignment
61. F43G9.5.F.1 in F43G9.5, transport (ortholog CBG12500) tree alignment
62. F49B2.5.F.6 in F49B2.5, intracellular signaling cascade; protein amino acid phosphorylation (ortholog CBG08738) tree alignment
63. F52E1.10.R.2 in F52E1.10, proton transport (ortholog CBG11248) tree alignment
64. F52H3.2.R.2 in F52H3.2, electron transport (ortholog CBG13376) tree alignment
65. F54C9.2.R.6 in F54C9.2, homolog of yeast stress-seventy subfamily A (ortholog CBG00564) tree alignment
66. F56F11.4A.F.2 in F56F11.4A, protein degradation (ortholog multiple) tree alignment
67. F56G4.5.F.3 in F56G4.5, electron transport (ortholog CBG08042) tree alignment
68. F57C2.5.R.1 in F57C2.5, biosynthesis (ortholog CBG20870) tree alignment
69. F57C2.5.R.2 in F57C2.5, biosynthesis (ortholog CBG20870) tree alignment
70. H17B01.1A.F.6 in H17B01.1A, carbohydrate transport (ortholog CBG07075) tree alignment
71. H27M09.1.F.7 in H27M09.1, homolog of yeast DEAD box RNA helicase (ortholog CBG12746) tree alignment
72. H27M09.1.F.8 in H27M09.1, homolog of yeast DEAD box RNA helicase (ortholog CBG12746) tree alignment
73. H43I07.2.F.2 in H43I07.2, transcription (ortholog CBG01436) tree alignment
74. K02A2.3.R.5 in K02A2.3, amino acid transport (ortholog CBG13060) tree alignment
75. K04D7.3.F.5 in K04D7.3, aminobutyrate metabolism (ortholog CBG03400) tree alignment
76. K05B2.3.R.6 in K05B2.3, homolog of human lamin (ortholog CBG14566) tree alignment
77. K08E3.1.F.3 in K08E3.1, metabolism (ortholog CBG18278) tree alignment
78. K08E3.1.F.5 in K08E3.1, metabolism (ortholog CBG18278) tree alignment
79. K10H10.1.F.3 in K10H10.1, transport (ortholog CBG00985) tree alignment
80. LLC1.1.R.3 in LLC1.1, proteolysis and peptidolysis (ortholog CBG21580) tree alignment
81. R07B7.1.R.5 in R07B7.1, chloride transport (ortholog CBG23365) tree alignment
82. R11E3.8.R.4 in R11E3.8, homolog of yeast dipeptidyl aminopeptidase (ortholog CBG11649) tree alignment
83. R13G10.1.R.2 in R13G10.1, chromosome segregation (ortholog CBG20143) tree alignment
84. R166.2.R.4 in R166.2, homolog of human cleft lip and palate protein (ortholog CBG03077) tree alignment
85. R74.1.R.3 in R74.1, amino acid activation; protein biosynthesis (ortholog CBG20159) tree alignment
86. T03F6.1.F.3 in T03F6.1, metabolism (ortholog CBG07035) tree alignment
87. T07A9.7.F.3 in T07A9.7, G-protein coupled receptor protein signaling pathway (ortholog CBG13491) tree alignment
88. T08G11.5.R.1 in T08G11.5, ion transport (ortholog CBG12389) tree alignment
89. T08G2.3.R.3 in T08G2.3, electron transport (ortholog CBG15946) tree alignment
90. T10B11.2.F.9 in T10B11.2, protein kinase C activation (ortholog CBG12724) tree alignment
91. T10F2.4.R.2 in T10F2.4, homolog of human nuclear matrix protein (ortholog CBG21324) tree alignment
92. T13H5.8.F.6 in T13H5.8, homolog of human cisplatin resistance related protein (ortholog CBG04750) tree alignment
93. T20B5.1.F.4 in T20B5.1, homolog of human adapter-related protein complex subunit (ortholog CBG16158) tree alignment
94. T23G5.2.R.4 in T23G5.2, transport (ortholog CBG10148) tree alignment
95. T26A5.3.F.5 in T26A5.3, electron transport (ortholog CBG19683) tree alignment
96. T26G10.1.R.1 in T26G10.1, homolog of yeast protein required for rRNA processing (ortholog CBG10097) tree alignment
97. T28F3.1A.R.2 in T28F3.1A, homolog of human copine V protein (ortholog CBG00380) tree alignment
98. W02D9.1.R.3 in W02D9.1, homolog of human DNA primase large subunit (ortholog CBG08720) tree alignment
99. W05E10.4.R.5 in W05E10.4, trehalose metabolism (ortholog CBG23281) tree alignment
100. W05E10.4.R.8 in W05E10.4, trehalose metabolism (ortholog CBG23281) tree alignment
101. W06D4.6.F.13 in W06D4.6, homolog of human DNA repair protein RAD54 (ortholog CBG12435) tree alignment
102. W06H3.1.F.4 in W06H3.1, homolog of human mitochondrial inner membrane protein (ortholog CBG24360) tree alignment
103. Y102A5A.1.F.9 in Y102A5A.1, homolog of yeast protein that is a member of the TIP120 family (ortholog CBG23895) tree alignment
104. Y22D7AL.5.F.2 in Y22D7AL.5, homolog of human heat shock protein (ortholog CBG11701) tree alignment
105. Y22D7AL.5.F.4 in Y22D7AL.5, homolog of human heat shock protein (ortholog CBG11701) tree alignment
106. Y25C1A.5.F.3 in Y25C1A.5, homolog of yeast protein involved in endoplasmic-to-Golgi protein trafficking (ortholog CBG19635) tree alignment
107. Y25C1A.5.F.5 in Y25C1A.5, homolog of yeast protein involved in endoplasmic-to-Golgi protein trafficking (ortholog CBG19635) tree alignment
108 Y37E11B.5.R.3 in Y37E11B.5, unknown function (ortholog CBG08326) tree alignment
109. Y38F2AR.2.F.1 in Y38F2AR.2, unknown function (ortholog CBG16815) tree alignment
110. Y42G9A.6.R.6 in Y42G9A.6, transport (ortholog CBG21117) tree alignment
111. Y43H11AL.3.R.10 in Y43H11AL.3, homolog of yeast sister chromatid cohesion protein (ortholog CBG07027) tree alignment
112. Y48G8AL.6.F.4 in Y48G8AL.6, RNA interference; nonsense-mediated decay; genital morphogenesis (ortholog CBG08494) tree alignment
113. Y50D4A.4.R.2 in Y50D4A.4, unknown function (ortholog CBG01087) tree alignment
114. Y50D7A.6.F.4 in Y50D7A.6, homolog of human kinesin-like protein (ortholog CBG15720) tree alignment
115. Y55F3AR.3.R.6 in Y55F3AR.3, homolog of human heat shock protein (ortholog CBG08425) tree alignment
116. Y59A8B.6.F.11 in Y59A8B.6, RNA processing: homolog of yeast RNA splicing factor (ortholog CBG05596) tree alignment
117. Y65B4A.6.R.2 in Y65B4A.6, homolog of human initiation factor (ortholog CBG05145) tree alignment
118. Y74C10AM.1.R.2 in Y74C10AM.1, transport (ortholog CBG03989) tree alignment
119. ZC404.9.R.2 in ZC404.9, protein amino acid phosphorylation (ortholog CBG19019) tree alignment
120. ZC410.3.R.1 in ZC410.3, N-linked glycosylation (ortholog CBG21758) tree alignment
121. ZK1320.6.F.1 in ZK1320.6, protein transport; signal transduction (ortholog CBG01059) tree alignment
122. ZK816.5.R.3 in ZK816.5, metabolism (ortholog CBG14194) tree alignment